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However, although an area may appear pigmented, the discoloration may not be related to actual pigment, but rather to the deposition or accumulation of organic or inorganic substances, including various metals and drug metabolites

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In: El Idrissi, A., L'Amoreaux, W

Angadi, PhD, Associate Professor of Kinesiology at UVAs School of Education and Human Development, wanted to better understand the potential long-term consequences of this muscle loss, so they reviewed available data on the drugs effects on cardiorespiratory fitness, or CRF